IGF-1 LR3 1mg & 0.1mg
Product Name: IGF-1 LR3 Available Strengths: 1mg, 0.1mg (100mcg) Full Name: Long R3 Insulin-Like Growth Factor-1 Alternative Names: Long R3 IGF-1, IGF-1 LR3, LR3-IGF-1 Research Category: IGF-1 Analog / Growth Factor Research Peptide Peptide Type: Synthetic Recombinant IGF-1 Analog Research Target: Insulin-Like Growth Factor 1 Receptor (IGF-1R) Research Interest: IGF-1 receptor signaling, cellular growth, protein synthesis pathways, glucose metabolism, cell proliferation, differentiation, and growth-factor biology. Description
IGF-1 LR3 is a modified analog of insulin-like growth factor-1 (IGF-1) developed for experimental research. Compared with native IGF-1, it contains an extended N-terminal sequence and an amino-acid substitution that alters its interaction with IGF-binding proteins. These modifications make IGF-1 LR3 useful for investigating IGF-related cellular and biochemical pathways. Structural Modification
IGF-1 LR3 contains an extended N-terminal region and an arginine substitution at position 3, from which the designation “Long R3” is derived. These structural modifications reduce its affinity for several IGF-binding proteins compared with native IGF-1 and alter its biological behavior in experimental systems. Mechanism of Research
IGF-1 LR3 primarily interacts with the insulin-like growth factor-1 receptor (IGF-1R), a receptor tyrosine kinase. Activation of IGF-1R initiates intracellular signaling pathways associated with cellular growth, proliferation, differentiation, survival, protein synthesis, and metabolic regulation. Research Applications
IGF-1 LR3 is used experimentally to investigate IGF-1 receptor biology, intracellular growth signaling, cellular proliferation and differentiation, protein-synthesis pathways, glucose metabolism, and interactions between growth factors and IGF-binding proteins. Storage
Storage requirements depend on the formulation and supplier. Research material should be stored according to the accompanying certificate of analysis (COA), product specification sheet, and manufacturer instructions. Research Use Disclaimer
IGF-1 LR3 is an investigational research compound and is not an approved therapeutic product. Information provided here is for scientific and research reference purposes only and should not be interpreted as medical, prescribing, or dosing advice. 
