AICAR 50mg

AICAR 50mg

Product Name: AICAR Strength: 50mg Research Category: AMPK Activator / Metabolic Research Compound Alternative Names: AICA Riboside, Acadesine, 5-Aminoimidazole-4-Carboxamide Riboside CAS Number: 2627-69-2 Molecular Formula: C₉H₁₄N₄O₅ Molecular Weight: Approximately 258.23 g/mol Compound Type: Synthetic Nucleoside Analog (Not a Peptide) Appearance: Typically supplied as a white to off-white research powder. Research Interest: AMPK signaling, cellular energy metabolism, glucose metabolism, lipid metabolism, mitochondrial function, and metabolic regulation.

Description

AICAR (5-aminoimidazole-4-carboxamide riboside) is an experimental nucleoside analog widely used in metabolic and cellular research. It is particularly studied for its relationship with AMP-activated protein kinase (AMPK), an important regulator of cellular energy homeostasis.

Mechanism of Research

After entering cells, AICAR can be phosphorylated to form ZMP (AICAR monophosphate), an AMP analog. ZMP can influence AMP-sensitive metabolic pathways, including activation of AMPK. Researchers use this mechanism to investigate cellular responses to changes in energy availability, glucose utilization, fatty-acid metabolism, and mitochondrial activity.

Research Applications

AICAR has been investigated in laboratory and preclinical studies involving energy metabolism, AMPK signaling, glucose uptake, fatty-acid oxidation, mitochondrial biology, and cellular responses to metabolic stress.

Storage

Storage requirements depend on the formulation and supplier. Research material should be stored according to the accompanying certificate of analysis (COA), safety data sheet (SDS), and manufacturer specifications.

Research Use Disclaimer

AICAR is a research compound and is not a peptide. This information is provided for scientific and research reference purposes only and should not be interpreted as medical, prescribing, or dosing advice.